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TDM Drug Dose Tables

The doses candidates tell us they cram every morning — organized by clinical area, taken from named Canadian sources, printable, and one click away from becoming spaced-repetition flashcards in your free account.

DrugIndicationDoseNotes
RamiprilHypertensionInitial 2.5 mg/day PO; usual 10 mg/day; max 20 mg/day (once daily or divided BID)ACEi — first-line in single-pill combo with a thiazide
PerindoprilHypertensionInitial 4 mg/day PO; max 8 mg/dayACEi
CandesartanHypertensionInitial 8 mg/day PO; usual 8–16 mg/day, once dailyARB — first-line in single-pill combo with a thiazide
LosartanHypertensionInitial 50 mg/day PO; usual 25–100 mg/day; max 100 mg/dayARB
AmlodipineHypertensionInitial 2.5 mg/day PO; max 10 mg/day, once dailyLong-acting DHP CCB — added as a third step after ARB + diuretic
HydrochlorothiazideHypertensionInitial 12.5 mg/day PO; usual 25 mg/day, once dailyReserve >25 mg/day for resistant hypertension
ChlorthalidoneHypertensionInitial 12.5 mg/day PO; usual 12.5–25 mg/day, once dailyThiazide-like diuretic
IndapamideHypertensionInitial 1.25 mg/day PO; usual 2.5 mg/day, once dailyThiazide-like diuretic
Irbesartan/HCTZHypertension — initial single-pill combinationStarting 150/12.5 mg once daily; may double after 4–6 wk if BP ≥130 systolicExample named initial combination; beta-blockers are NOT first-line without another indication

Source: CPS — Hypertension (rev. Jan 6, 2026)

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For exam preparation only. Doses are transcribed from the Canadian sources named on each table and simplified for study — always verify against the current product monograph and full guideline before any clinical use.